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5+ Clubs Open On Thursday In Prague (2025 Update)

Thursday nights in Prague just got more exciting. Check out this guide to the best clubs for a midweek party.

Written by Tereza Nováková

Updated on January 1, 2025

Are you looking for a fun escape? Imagine being in Prague, where every Thursday night brings exciting adventures in the city’s coolest clubs.

Check out our guide to find luxury and excitement in the nightlife. Whether you love fancy lounges or lively underground parties, we have something for everyone. Your Thursday nights are about to get amazing.

Join us in places where great music, fun people, and an awesome vibe come together for unforgettable nights. From the second you walk in, you'll enjoy amazing drinks, meet cool people, and dive into fun settings. Let us introduce you to the heart of Prague's nightlife, where every Thursday is the start of something new. Ready to change your Thursdays? Let’s go.

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Interior of M1 Lounge and Club Prague featuring a vibrant bar with blue lighting, plush seating, and a bustling atmosphere.

Photo credits: M1 Lounge and Club

(4.5)

1. M1 Lounge and Club

What is it? M1 Lounge and Club is the heartbeat of Prague's nightlife, filled with non-stop dancing and memorable moments. It's a top spot for anyone looking for the best night out, thanks to its lively energy and mix of global music.

Why we love it: More than just its great spot in the city or its cool look, M1 Lounge and Club wins our hearts because it brings different people together to enjoy amazing beats. Top DJs play everything from pop to deep house, making sure there's something for everyone. Dive into Prague's party life here and make unforgettable memories. Feel the vibe, dance the night away, and collect stories to tell for years to come.

Sunday, Monday, Tuesday, Wednesday, Thursday, Friday, Saturday

1, Masná 705, 110 00 Prague

Vibrant nightclub scene at Epic Prague, featuring a lively crowd, dynamic lighting displays, and smoke effects.

Photo credits: Epic Prague

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2. Epic Prague

What it is: Epic Prague is the top spot for nightlife in the city, located at Revoluční 1003/3. It's a place filled with amazing sounds, lights, and beats.

Why we love it: This nightclub is magical. It's both stylish and wild, making sure you dance all night long to great music played by top DJs. Epic Prague is a mix of both locals and visitors, creating a fun and lively atmosphere. It's where new friends meet and unforgettable memories are made. Every trip to Epic Prague is a story you'll want to share.

Wednesday, Thursday, Friday, Saturday

Revoluční 1003/3, 110 00 Prague

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Vibrant nightclub with purple lighting, plush seating, and a well-stocked bar area under a stone vaulted ceiling.

Photo credits: INDUSTRY Prague

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3. INDUSTRY Prague

What is it? Discover INDUSTRY Prague, the lively heart of Prague's nightlife. Located at Malá Štupartská 3, this place mixes cool modern vibes with a tough industrial look. It's both trendy and welcoming.

Why we love it: As soon as you enter, INDUSTRY Prague dazzles you with bright neon lights and buzzing energy. The music, from popular hits to EDM, feels alive thanks to an amazing sound system. It's a mix of locals, travelers, and party lovers all enjoying a great night. INDUSTRY Prague means fun memories, endless excitement, and letting loose on the dance floor.

Sunday, Monday, Tuesday, Wednesday, Thursday, Friday, Saturday

Malá Štupartská 3, 110 00 Prague

Sleek and modern Moonclub Prague featuring a stylish bar with golden accents under arched ceilings and ambient lighting.

Photo credits: MOONCLUB

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4. MOONCLUB

What is it? MOONCLUB is Prague's top spot for nightlife. Dive into a world of fun where music and vibes meet, making every night in Prague's center unforgettable.

Why we love it: MOONCLUB has an exciting vibe, with amazing visuals and top-notch sound getting the dance floor going. It's where trendsetters and travelers come together, enjoying music from house to hip-hop, picked by famous DJs. Here, it's all about connecting, dancing, and making memories that stay with you.

Wednesday, Thursday, Friday, Saturday

Dlouhá 709/26, 110 00 Prague

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Radost Fx Prague

Photo credits: Radost FX

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5. Radost FX

What is it? Radost FX Prague is more than a club. It's your ticket to an amazing night right in the city's heart. This club glows with neon lights, inviting you to a world of fun and excitement.

Why we love it: It's where music touches your heart. The best DJs play house, techno, and electronic beats here. Radost FX brings together cool styles, creativity, and pure happiness. It draws a mix of people all ready to dance till dawn. Whether it's your first time or you're back for more, Radost FX gives you nights full of beats, energy, and friendly faces. Discover your rhythm at Radost FX Prague and create lively memories.

Thursday, Friday, Saturday

Bělehradská 234/120, 120 00 Prague

Final word

As we explored Prague's buzzing nightlife and found the top 5+ clubs open on Thursdays in 2025, it's clear: every Thursday, the city turns into a huge party. Prague is calling you for an amazing time, with clubs playing all kinds of music and spaces that impress everyone. With this guide, you're ready to jump into the city's night scene, finding places that match your taste in music and vibe. The magic of Prague's nightlife is just a step away, ready to make your trip unforgettable. So why wait? Follow the music and see what these awesome clubs have to offer. And if you want more, our travel blog is full of tips and ideas to make your adventures even better. Join us, and let Prague's nightlife be the start of your exploration.

Nox Difference

Reserve with Nox to get exclusive access to the finest venues and insider tips.

Priority Access

Reserve 2,000+ venues worldwide.

Your Own Concierge

Get custom, curated recommendations.

VIP Experience

Enjoy special service.

Guide

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