Ask your Concierge

RomeBest PlacesGuidesReservationsConciergeMembership
Partner with usSign up
Room 26 Rome

Photo credits: Room 26 Rome

15+ Clubs Open On Saturday In Rome (2025 Update)

Rome never sleeps. Pick your spot, dive in, and dance till dawn. Every Saturday promises a new adventure. Ready to explore?

Written by Giulia Bianchi

Updated on January 1, 2025

Ever dreamed of dancing in Rome, surrounded by ancient charm and modern vibes? Picture moving to the beat in beautifully crafted clubs, each mixing old Roman beauty with new luxury. Our 2025 guide takes you to Rome's top Saturday night spots. We've picked over 15 exclusive clubs for you. Want high-energy dance floors or cozy lounges with unique cocktails? Our guide has it all, for every taste, offering a luxury trip into Rome's best nightlife circles. Ready to see where Rome's nightlife shines brightest? Join us to make unforgettable memories in the city's most exciting and stylish places. Let's dive into this amazing journey together.

Nox Difference

Reserve with Nox to get exclusive access to the finest venues and insider tips.

Priority Access

Reserve 2,000+ venues worldwide.

Your Own Concierge

Get custom, curated recommendations.

VIP Experience

Enjoy special service.

Guide
Vibrant nightclub scene at Art Cafe Rome with a crowd enjoying live performances and dynamic lighting.

Photo credits: Art Cafe

(4.6)

1. Art Cafe

What is it? The Art Cafe is the top spot for nightlife in Rome. It's a go-to place for a great time in this famous city.

Why we love it: It's more than just a club; it's an adventure. The best DJs play all kinds of music, so every night is special. The Art Cafe is known for its fun theme parties, making each visit unique. It mixes great music with cool vibes, offering a fun experience that's different from the usual.

Thursday, Friday, Saturday

Viale del Galoppatoio, 197 Rome

Lively Rome nightclub atmosphere with cozy vintage sofas, vibrant red neon lights, and exotic plants under a dim, moody lighting.

Photo credits: Circolo Degli Illuminati

(4.5)

2. Circolo Degli Illuminati

What is it? Circolo Degli Illuminati isn't just any nightclub. It's a special spot in Rome where you can enjoy calm drinks, delicious meals, or dance the night away. Located in the heart of Via Giuseppe Libetta, this place is buzzing with energy every day.

Why we love it: It's unique because it's stylish and plays great music, from house to techno, keeping the dance floor packed. It's a welcoming place for everyone, from locals and tourists to famous people and VIPs. Circolo Degli Illuminati offers unforgettable nights in Rome.

Sunday, Thursday, Friday, Saturday

1 Via Giuseppe Libetta, 00154 Rome

Do you want personalized recommendations and exclusive access to the finest experiences? Get your personalized plan now.

A female DJ controls the decks at The Sanctuary Rome, surrounded by an energetic crowd under ambient, hexagonal lighting.

Photo credits: The Sanctuary

(4.4)

3. The Sanctuary

What is it? Welcome to The Sanctuary, a special spot in the heart of Rome where Mexico's lively vibes meet Thailand's calm soul. It's more than just a place to go out at night; it's a taste, sound, and spirit adventure. Try the Tropic-Asian Restaurant for dishes full of stories from ancient times.

Why we love it: The Sanctuary stands out in Rome's busy scene. It's unique because you can enjoy top-notch food, dance to worldwide music, and relax with massages and yoga all in one place. It's a creative and joyful spot that draws people from everywhere. Visit for a great adventure and make lasting memories.

Sunday, Thursday, Friday, Saturday

4A Via delle Terme di Traiano, 00184 Rome

DJ playing at a bustling nightclub with a lively crowd and vibrant lights.

Photo credits: Room 26

(4.4)

4. Room 26

What's it about? Discover Rome's top spot for nightlife at Room 26. Enjoy top DJs, cool sound, and stylish vibes. It's the place where style meets fun, making everyone feel included.

Why we love it: Room 26 shines in Rome's famous Piazza Guglielmo Marconi, setting it apart from ordinary clubs. Its mix of house, hip hop, and techno, plus a lively crowd, makes for an unforgettable night. Hang out with friends or go solo; either way, Room 26 promises nights you'll remember long after the party ends.

Thursday, Friday, Saturday

29/31 Piazza Guglielmo Marconi, 00144 Rome

Do you want personalized recommendations and exclusive access to the finest experiences? Get your personalized plan now.

Elegant nighttime dining setup at Profumo Spazio Sensoriale nightclub in Rome featuring tables adorned with candles under a canopy of twinkling lights on an olive tree.

Photo credits: Profumo Spazio Sensoriale

(4.4)

5. Profumo Spazio Sensoriale

What is it? Profumo Spazio Sensoriale is a special place in Rome, on Via di Villa Lauchli. It's not just a nightclub. It's also a restaurant, lounge bar, and event space, all set in a beautiful garden.

Why we love it: Profumo is like a dream with its beautiful flowers and garden. It's perfect for evening walks. The food is full of Mediterranean flavors, and the drinks list has both classic and new cocktails. It's a stylish and relaxing spot, great for a quiet dinner, a romantic date, or a fancy party. Profumo is where you make memories to keep.

Sunday, Tuesday, Wednesday, Thursday, Friday, Saturday

1 Via di Villa Lauchli, 00191 Rome

Luxurious nightlife ambiance at NOTORIOUS Rome with vibrant lighting over plush blue seating and ornate carpeting, inviting an unforgettable evening.

Photo credits: NOTORIOUS

(4.3)

6. NOTORIOUS

What it is: NOTORIOUS is the top spot for nightlife in Rome, shining bright for over 40 years. Right in the heart of Rome, this club is where fun lovers go to make unforgettable memories.

Why we love it: NOTORIOUS is more than just a club. It blends classic style with modern touches. Here, you'll find cozy seats and top-notch sound, creating a perfect vibe. Whether you're dancing your heart out or chilling in a VIP area, it offers both excitement and comfort. This is where Rome's party scene comes alive, turning every visit into a memorable adventure.

Friday, Saturday

22 Via di San Nicola da Tolentino, 00187 Rome

Do you want personalized recommendations and exclusive access to the finest experiences? Get your personalized plan now.

Vibrant nightclub scene at Jolie Club Rome featuring a server carrying a champagne bottle with sparklers, surrounded by a lively crowd under dim, starry lights.

Photo credits: Jolie Club

(4.3)

7. Jolie Club

What it is: Jolie Club in Rome is the top spot for a night full of dancing and fun. It's in the middle of Rome's lively night scene at 13 Via Velletri. The club's cool, updated look is perfect for any big night out.

Why we love it: It's more than a club; it's a whole experience. The soft, mood-lifting lights and great sound system make Jolie Club buzz with energy. You'll find Rome's best DJs here, playing all kinds of music. The crowd is a great mix of both locals and tourists, giving it a friendly, global vibe. Whether you always hit the dance floor or you're new to clubs, Jolie Club will give you nights to remember.

Friday, Saturday

13 Via Velletri, 00198 Rome

Piper Club Rome

Photo credits: Piper Club

(4.3)

8. Piper Club

What is it? The Piper Club is a famous club in the heart of Rome. It welcomes up to 1500 guests, mixing local charm with worldwide vibes.

Why we love it: It's more than a club; it's a historic spot full of fun. It has a big dance area, private spots, and a busy bar, perfect for all kinds of parties. Stars like Pink Floyd and The Who have rocked its stage, making it a place of unforgettable nights. Looking for a wild weekend or a big event? The Piper Club is your go-to for a great night out.

Friday, Saturday

Via Tagliamento, 198 Rome

Do you want personalized recommendations and exclusive access to the finest experiences? Get your personalized plan now.

Toy Room Rome

Photo credits: Toy Room

(4.3)

9. Toy Room

What is it? Toy Room, a top nightclub in Rome, catches everyone's eye. Big stars like Leonardo DiCaprio and Rihanna love it here, and it's famous worldwide.

Why we love it: Toy Room stands out in Rome's nightlife. Its cool design invites everyone into a world of fun like no other, offering all kinds of experiences. Every night is a mix of timeless appeal and exciting vibes. With so many great events, booking a table means you're in for memorable nights. Step into Toy Room, where amazing moments happen.

Sunday, Friday, Saturday

Via degli Avignonesi, 187 Rome

Elegant dining setup at Jackie O' Rome Nightclub, featuring tables adorned with white linens, glowing candles, and yellow floral arrangements, set against a backdrop of sophisticated dark interiors with patterned walls and vibrant artwork.

Photo credits: Jackie O'

(4.1)

10. Jackie O'

What is it? Jackie O' is your key to Rome's exciting night scenes and amazing food. It's close to famous places like Via Vittorio Veneto and Piazza di Spagna. This place shines with its fancy design, great meals, and live music from Tuesday to Saturday.

Why we love it: For over 50 years, Jackie O' has been the place to be in Rome, mixing style, fun, and special moments. Whether you're celebrating or just out for the night, it offers special menus, great service, and private rooms for an experience full of luxury. Be part of the cool crowd, feel the magic, and create memorable times. Book your spot of glamour at Jackie O'.

Tuesday, Wednesday, Thursday, Friday, Saturday

11 Via Boncompagni, 00187 Rome

Do you want personalized recommendations and exclusive access to the finest experiences? Get your personalized plan now.

A vibrant scene at Alcazar nightclub in Rome with a crowd enjoying a live performance under a glowing disco ball and neon lights.

Photo credits: ALCAZAR

(4)

11. ALCAZAR

What is it? ALCAZAR in Rome is more than just a nightclub. It's a lively mix of music, art, theater, and fine food. It's full of energy, attracting both locals and travelers who want to experience some culture and fun.

Why we love it: ALCAZAR is a treat for all your senses. It has everything from live jazz, art shows, classic movies, to creative food. It's all set in a cool, old cinema. It's perfect for a fun night out or an unforgettable corporate event. ALCAZAR gives you memorable moments that will stick with you.

Sunday, Thursday, Friday, Saturday

14 Via Cardinale Merry del Val, 00153 Rome

Shari Vari Rome

Photo credits: Shari Vari

(3.8)

12. Shari Vari

What is it? Shari Vari in Rome is the spot where music beats meet the city's heart. From hip hop to electric tunes, it's alive. World-class DJs spin mixes that keep the energy up and people moving. Every night, Tuesday to Sunday, offers a new musical adventure.

Why we love it: Shari Vari isn't just any nightclub; it's a haven for music. It has a big dance floor and a stylish bar. It welcomes everyone into a world where each room has its own beat. Here, you're not just dancing; you're on a musical journey. It's where the night comes alive.

Sunday, Tuesday, Wednesday, Thursday, Friday, Saturday

Via di Torre Argentina, 186 Rome

Do you want personalized recommendations and exclusive access to the finest experiences? Get your personalized plan now.

Final word

In the heart of Rome, Saturday night lights up with music and fun. Over 15 clubs are ready to make your night exciting. From small, cozy spots to big dance halls, there's something for everyone. If you love clubbing or just want to try it, Rome's clubs will give you an amazing night under the stars. This guide shows you the most exciting places to experience Rome's lively nightlife. Don't miss out on the fun – Rome's clubs are waiting for you. Want to find more great night spots? Our blog has all the best tips to make your nights in Rome unforgettable.

Nox Difference

Reserve with Nox to get exclusive access to the finest venues and insider tips.

Priority Access

Reserve 2,000+ venues worldwide.

Your Own Concierge

Get custom, curated recommendations.

VIP Experience

Enjoy special service.

Guide

You may also like

10+ Clubs Open On Sunday In Rome (2025 Update)

5+ Clubs Open On Monday In Rome (2025 Update)

5+ Clubs Open On Tuesday In Rome (2025 Update)

5+ Clubs Open On Wednesday In Rome (2025 Update)

10+ Clubs Open On Thursday In Rome (2025 Update)

15+ Clubs Open On Friday In Rome (2025 Update)

Make it Easy

Get access to our smart platform that organizes your travels, secures your reservations, organizes your day, and connects you to the world’s best experiences, powered by AI & Concierge Experts.

Alotea Concierge